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In a blog post on Percona, the author discusses the popularity of UUIDs (Universally Unique Identifiers) in the context of databases, highlighting their negative impact on performance. UUIDs are often used as primary keys because of their uniqueness, but it turns out that their integration into systems brings with it performance challenges. The implementation of UUIDs increases index size, leading to a decrease in query speed and a higher burden on memory. The author also touches on issues such as database fragmentation and difficulties in optimizing queries using UUIDs. The central message of the article is the need to reconsider the use of UUIDs, especially when performance is critical. Readers are encouraged to explore alternative methods for generating unique keys to better utilize system resources and improve application response times.